2021 Differential usage of transcriptional repressor Zeb2 enhancers distinguishes adult and embryonic hematopoiesis. Our team includes specialists in epilepsy, genetic pharmacology, immunological research, clinical research and more. Interactions between tetracyanoquinodimethane (TCNQ) and two typical silver clusters Ag13 and Ag20 are studied by first-principles DFT. Huang X, Ferris ST, Kim S, Choudhary MNK, Belk JA, Fan C, Qi Y, Sudan R, Xia Y, Desai P, Chen J, Ly N, Shi Q, Bagadia P, Liu T, Guilliams M, Egawa T, Colonna M, Diamond MS, Murphy TL, Satpathy AT, Wang T, Murphy KM. 2022 cDC1 vaccines drive tumor rejection by direct presentation independently of host cDC1. PMCID: PMC10336151įerris ST, Ohara RA, Ou F, Wu R, Huang X, Kim S, Chen J, Liu TT, Schreiber RD, Murphy TL, Murphy KM. 2023 IL-6 selectively suppresses cDC1 specification via C/EBPβ. Kim S, Chen J, Jo S, Ou F, Ferris ST, Liu TT, Ohara RA, Anderson DA, Wu R, Chen MY, Gillanders WE, Gillanders WE, Murphy TL, Murphy KM. 2023 WDFY4 deficiency in NOD mice ameliorates autoimmune diabetes and insulitis. My work in the Murphy lab will seek to better understand DC development-specifically the molecular genetic circuitries and transcriptional requirements driving lineage-differentiation.įerris ST, Liu T, Chen J, Ohara RA, Ou F, Wu R, Kim S, Murphy TL, Murphy KM. Jing Yi Chen Wen-Chun Hung 1alpha,25-dihydroxyvitamin D3 (vitamin D3) has been shown to upregulate p27Kip1 expression via Sp1 and NF-Y binding sites in the p27Kip1 promoter. cDC1s are uniquely important in response against intracellular pathogens and tumors due to their ability to cross-present antigens. The two branches of DCs consists of plasmacytoid DCs (pDCs) and classical DCs (cDCs), of which can be further subdivided into cDC1s and cDC2s. Undergraduate university: New York University, 2018ĭendritic cells (DCs) functions to bridge innate and adaptive immunity by mediating the activity of various effector cells.
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